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Sequencer Simulation Functions

• NextGenSeqUtils.env_pb_seq_sim
• NextGenSeqUtils.fixed_diff_evolve
• NextGenSeqUtils.pb_seq_sim
• NextGenSeqUtils.simple_evolve
• NextGenSeqUtils.simple_gen_seq

# NextGenSeqUtils.simple_gen_seq — Function.

simple_gen_seq(n::Int)

Generates a random uniform sequence of nucleotides.

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# NextGenSeqUtils.simple_evolve — Function.

simple_evolve(refseq, err_rate)

Evolves a sequence, uniformly.

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# NextGenSeqUtils.fixed_diff_evolve — Function.

fixed_diff_evolve(template::String, n_diffs::Int64)

Creates a fixed number of mutations of a sequence.

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# NextGenSeqUtils.pb_seq_sim — Function.

pb_seq_sim(template::String, rate::Float64; with_qvs = false)

Performs a sequence simulation from a template, specifying a target error rate, based on PacBio sequencing error model.

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# NextGenSeqUtils.env_pb_seq_sim — Function.

env_pb_seq_sim(template::String, n::Int64; with_qvs = false)

Simulated PacBio reads from amplicons that have envelope-like error profiles.

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